Department of Orthopaedic Surgery

MaCalus V. Hogan, MD, MBA

  • Associate Professor
  • Vice Chair of Education and Residency Program Director
  • Chief, Foot and Ankle Division
  • Senior Medical Director, UPMC Health Plan Orthopaedic and Musculoskeletal Care Services
  • Medical Director of Outcomes, UPMC Wolff Center for Quality, Safety and Innovation

Education & Training

  • MD, Howard University College of Medicine, Washington, D.C.
  • Residency: University of Virginia Medical School, Charlottesville, VA
  • Fellowship: Hospital for Special Surgery, New York, NY
  • MBA, University of Pittsburgh, Joseph M. Katz Graduate School of Business

Representative Publications

  1. Pitcairn S, Kromka J, Hogan M, Anderst W. Validation and Application of Dynamic Biplane Radiography to Study In Vivo Ankle Joint Kinematics During High-Demand Activities. J Biomech. 2020 Apr :109696. PMID: 32139098
  2. Patel NK, Murphy CI, Pfeiffer TR, Naendrup JH, Zlotnicki JP, Debski RE, Hogan MV, Musahl V. Sagittal instability with inversion is important to evaluate after syndesmosis injury and repair: a cadaveric robotic study. J Exp Orthop. 2020 Mar;7(1):1-7. PMID: 32232587
  3. Canton S, Anderst W, Hogan MV. In Vivo Ankle Kinematics Revealed Through Biplane Radiography: Current Concepts, Recent Literature, and Future Directions. Curr Rev Musculoskelet Med. 2020 Jan 27:1-9. PMID: 31989528
  4. Li H, Sun H, Qian B, Feng W, Carney D, Miller J, Hogan MV, Wang L. Increased expression of FGF‐21 negatively affects bone homeostasis in dystrophin/utrophin double knock‐out mice. J Bone Miner Res. 2019 Dec 4. PMID: 31800971
  5. Dombrowski M, Murawski CD, Yasui Y, Chen AF, Ewalefo SO, Fourman MS, Kennedy JG, Hogan MV. Medical comorbidities increase the rate of surgical site infection in primary Achilles tendon repair. Knee Surg Sports Traumatol Arthrosc. 2019 Sep 1;27(9):2840-2851. PMID: 30663002
  6. Hattori S, Alvarez CAD, Canton S, Hogan MV, Onishi K.  Ultrasound-Guided Ankle Lateral Ligament Stabilization. Curr Rev Musculoskeletal Med. 2019 Nov. Pub Online. PMID: 31749104
  7. Dombrowski M, Murawski CD, Yasui Y, Chen AF, Ewalefo SO, Fourman MS, Kennedy JG, Hogan MV. Medical Comorobidities Increase the Rate of Surgical Site infection in Primary Achilles Tendon Repair. Knee Surg Sports Traumatol Arthrosc. 2019 Sep;27(9):2840-2851. PMID: 30663002
  8. Mittwede PN, Morales-Restrepo A, Forurman MS, Fu FH, Lee JY, Ahn J, Egol KA, Hogan MV. Research-Track Residency Programs in Orthopaedic Surgery: A Survey of Program Directors and Recent Graduates. J Bone Joint Surg Am. 2019 Aug 7;101(15):1420-1427. PMID: 31393436
  9. Zhang J, Nie D, Williamson K, Rocha JL, Hogan MV, Wang JH. Selectively Activated PRP Exerts Diferential Effects on Tendon Stem/progenitor Cells and Tendon Healing. J Tissue Eng. 2019 Jan 16;10:2041731418820034. PMID: 30728936
  10. Ewalefo SO, Dombrowski M, Hiras T, Rocha JL, Weaver M, Kline A, Carny D, Hogan MV. Management of Posttraumatic Ankle Arthritis: Literature Review.2018 Dec; 11(4):546-557; PMID: 30327933
  11. Hogan MV, Hicks JJ, Chambers MC, Kennedy JG. Biologic Adjuvants for the Management of Osteochondral Lesions of the Talus. J Am Acad Orthop Surg. 2018 Nov [Epub ahead of print]; PMID: 30431502
  12. Zhang J, Nie D, Rocha JL, Hogan MV, Wang JHC. Characterization of the structure, cells and cellular mechanobiological response of human plantar fascia. Journal of Tissue Engineering. 2018 Sept; PMID: 30302189
  13. Dombrowski ME, Yasui Y, Murawski CD, Fortier L, Giza E, Haleem AM, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Conservative Management and Biological Treatment Strategies: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot & Ankle International. 2018 Jul; Vol 39 (1_suppl), 9S-15S. PMID: 30215314
  14. Van Dijk PAD, Murawski CD, Hunt KJ, Andrews CL, Longo UG, McCollum G, Simpson H, Sofka CM, Yoshumura I, Karlsson J, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Post-treatment Follow-up, Imaging, and Outcome Score: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):68S-73S. PMID: 30215316
  15. Mittwede PN, Murawski CD, Ackerman J, Gortz D, Hintermann B, Kim HJ, Thoradson DB, Vannini F, Younger ASE, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Revision and Salvage Management: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):54S-60S. PMID: 30215315
  16. D’hooghe P, Murawski CD, Boakye LT, Osei-Hwedieh DO, Drakos MC, Hertel J, Lee KB, Popchak A, Wiewiorski M, Van Dijk CN, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Rehabilitation and Return to Sports: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):61S-67S. PMID: 30215313
  17. Rothrauff BB, Murawski CD, Angthong C, Becher C, Nehrer S, Niemeyer P, Sullivan M, Valderrabano C, Walther M, Ferkel RD, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Scaffold-Based Therapies: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):41S-47S. PMID: 30215312
  18. Shimonzo Y, Brown AJ, Batista JP, Murawski CD, Gomaa M, Kong SW, Vaseenon T, Takao M, Glazebrook M, Hogan MV; Subchondral Pathology: Proceedings of the International Consensus meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):48S-53S. PMID: 30215311
  19. Reilingh ML, Murawski CD, DiGiovanni CW, Dahmen J, Ferrao PNF, Lambers KTA, Ling JS, Tanaka Y, Kerkhoffs GMMJ, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Fixation Techniques: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):23S-27S. PMID: 30215310
  20. Hurley ET, Murawski CD, Paul J, Marangon A, Prado MP, Xu X, Hangody L, Kennedy JG, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Osteochondral Autograft: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):28S-34S. PMID: 30215309
  21. Smyth NA, Murawski CD, Adams SB Jr, Berlet GC, Buda R, Labib SA, Nunley JA 2nd, Raikin SM, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Osteochondral Allograft: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):35S-40S. PMID: 30215308
  22. Hannon CP, Bayer S, Murawski CD, Canata GL, Clanton TO, Haverkamp D, Lee JW, O’Malley MJ, Yinghui H, Stone JW, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Debridement, Curettage, and Bone Marrow Stimulation: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):16S-22S. PMID: 30215307
  23. Van Bergen CJA, Baur OL, Murawski CD, Spennacchio P, Carreira DS, Kearns SR, Mitchell AW, Pereira H, Pearce CJ, Calder JDF, Hogan MV; International Consensus Group on Cartilage Repair of the Ankle. Diagnosis: History, Physical Examination, Imaging, and Arthroscopy: Proceedings of the International Consensus Meeting on Cartilage Repair of the Ankle. Foot Ankle Int. 2018 Jul; 39(1_suppl):3S-8S. PMID: 30215306
  24. Zhou S, Qian B, Wang L, Zhang C, Hogan MV, Hongshuai L.  Altered Bone-Regulating Myokine Expression in Skeletal Muscle of Duchenne Muscular Dystrophy Mouse Models. Muscle Nerve. 2018 Jul; 58(4):573-582 PMID 30028902
  25. Zhao E, Carney D, Chambers M, Hogan MV. The role of biologic in foot and ankle trauma—a review of the literature. Curr Rev Musculoskelet Med. 2018 Jul; 11(3):495-502. PMID: 30054808
  26. Zhang J, Yuan T, Zheng N, Zhou Y, Hogan MV, Wang JHC. The Combined Use of Kartogenin and PRP Promotes Fibrocartilage Formation in Wounded Rat Achilles Tendon Entheses. Bone and Joint Research. 2017 April; PMID 28450316
  27. Zhou Y, Zhang J, Yang J, Narava M, Zhao G, Yuan T, Wu H, Zheng N, Hogan MV, Wang JHC. Kartogenin with PRP Promotes the Formation of Fibrocartilage Zone in the Tendon-Bone Interface. J Tissue Eng Regen Med. 2017 Jan; PMID 28127950.
  28. Li H, Lu A, Tang Y, Beckman S, Nakayama N, Poddar M, Hogan MV, Huard J. The Superior Regenerative Potential of Muscle Derived Stem Cells for Articular Cartilage Repair is Attributed to High Cell Survival and Chondrogenic Potential. Molecular Therapy - Methods & Clinical Development Osteoarthritis Cartilage. 2016 Nov; PMID: 27990446.
  29. Atesok K, Satava RM, Van Heest A, Hogan MV, Pedowitz RA, Fu FH, Sitnikov I, Marsh JL, Hurwitz SR. Retention of Skills After Simulation-based Training in Orthopaedic Surgery. J Am Acad Orthop Surg. 2016 Jun. [Epub ahead of print] PubMed PMID: 27348146.
  30. Ferguson C, Rocha JL, Lalli T, Irrgang JJ, Hogan MV. Developing Performance Assessment Platforms in Foot and Ankle Surgery. Foot and Ankle International. 2016 May; PMID: 27177887
  31. Hicks J, Oyster N, Reyna R, Philippon MJ, Hurwitz SR, Hogan MV, Huard J, Li H. Customized Platelet-Rich Plasma with TGF-β1 Neutralization Antibody to Reduce Fibrosis in Injured Skeletal Muscle. Biomaterials. 2016 May; PMID: 26923362
  32. Hutchinson ID, Baxter JR, Gilbert S, Hogan MV, Ling J, Saunders SM, Wang H, Kennedy JG. The Effects of Hindfoot Fusion Modalities on Ankle Biomechanics During Standing. Clin Ortho and Related Res. 2016 April; PMID: 26689585
  33. Hogan MV, Mani SB, Chan JS, Lyman S, Huong Do, Deland JT, Ellis SJ. Validation of the Foot and Ankle Outcome Score for Hallux Rigidus. HSS Journal. 2016 Feb; PMID 26855627
  34. Kennedy JG, Ross KA, Smyth NA, Hogan MV, Murawski CD. Primary Tumors of the Foot and Ankle. Foot and Ankle Spec. 2016 Feb; PMID: 26644034
  35. Hannon CP, Ross KA, Murawski CD, Deyer TW, Smyth NA, Hogan MV, Do HT, O'Malley MJ, Kennedy JG. Arthroscopic Bone Marrow Stimulation and Concentrated Bone Marrow Aspirate for Osteochondral Lesions of the Talus: A Case-Control Study of Functional and Magnetic Resonance Observation of Cartilage Repair Tissue Outcomes. Arthroscopy. 2016 Feb; PMID: 26395409

PubMed Link

Research Interests

Serves as Director of the Foot and Ankle Injury Research [F.A.I.R.] Group and co-director of the Musculoskeletal Growth Regeneration Lab, with Dr. Hongshai Li.  My research involves regenerative bioengineering using stem cells and biomaterials, the biomechanical assessment of foot and ankle injuries and fixation techniques, as well as clinical outcomes research.  We have presented our research both nationally and internationally. Our research team has received the American Orthopaedic Foot and Ankle Society (AOFAS) J. Leonard Goldner Award for best basic science research for work on tendon regeneration entitled:  “Successful Achilles Tendon Regeneration using a Bioresorbable Nanofiber Scaffold, Stem Cells, and Growth Factor in a Rat Tendon Gap Defect Model.”   In addition to my clinical and research practice, I serve as the foot and ankle consultant for the athletic departments at the University of Pittsburgh, Carnegie Mellon University, and Duquesne University, and also serve as the Assistant Team Physician for Point Park University and the Conservatory of Performing Arts.  Dr. Hogan has been named yearly to Best Doctors in America® since 2016.

Research Grants

  1. The Role of the Syndesmosis in Ankle Joint and Tibiofibular Kinematics
    Grant Number:  n/a
    Time Commitment: n/a Role:  PI
    Supporting Agency:  American Orthopaedics Foot & Ankle Society, 9400 W. Higgins Road, Suite 220, Rosemont, IL 60018
    Performance Period: 07/01/17 – 06/30/18 [NCE]
    Level of Funding:  $20,000
     
  2. Adult Stem Cell-Based Enhancement of Nerve Conduit for Peripheral Nerve Repair
    Grant Number:  W81XWH-15-1-0600
    Time Commitment:  1.20 calendar months (10%) during half of year 2, and all of year 3.
    Role:  Co-Investigator
    Supporting Agency: Department of Defense, 820 Chandler Street, Fort Detrick MD, 21702-5014
    Performance Period:  09/30/15 – 09/29/18 [NCE]
    Level of Funding:  $1,557,090
     
  3. Novel Mg Alloy Based Biodegradable Porous Scaffolds for Bone Regeneration of Critical Sized Cranial Bone Defects
    Grant Number: n/a
    Time Commitment: 10%
    Role: Co-Investigator
    Supporting Agency: The Musculoskeletal Transplant Foundation
    Performance Period: 07/01/2017 – 06/30/2018 [NCE]
    Level of Funding: $100,000
     
  4. Integrated Clinical and Research Systems for Diabetic Foot Wound Care
    Grant Number: 1U01DK119102
    Time Commitment:
    Role: Co-Investigator
    Supporting Agnecy:
    Performance Period: 09/15/2018-06/30/2022
    Level of Funding: $275,000