Department of Orthopaedic Surgery

Jonathan D. Hughes, MD

  • Clinical Instructor
  • Team Physician, Pitt Football

Clinical Interests Include:

  • Shoulder Arthroscopy and Complex Shoulder Procedures Including Arthroplasty, Arthroscopic and Open Instability Repair, Rotator Cuff Repair and Reconstruction, AC Joint Reconstruction, Clavicle and Proximal Humerus Fracture Fixation
  • Knee Arthroscopy and Complex Knee Procedures Including Multi-Ligament Reconstruction, Revision Ligament Reconstruction, Tendon Repairs and Reconstruction, Extra-Articular Tenodesis, Patellar Instability, Patella Fracture Fixation, Cartilage Restoration, Osteotomies
  • Open Elbow Procedures Including Tendon Repair and Reconstruction, Collateral Ligament Repair and Reconstruction, Cartilage Restoration

Education & Training

  • MD, University of Texas Health science Center at San Antonio, San Antonio, TX
  • Residency: Baylor Scott and White Healthcare-Temple, Temple, TX
  • Fellowship: University of Pittsburgh Medical Center, Pittsburgh, PA

Representative Publications

  • Winkler PW, Zsidai B, Wagala N, Hughes JD, Horvath A, Senorski EH, Samuelsson K, Musahl V. “Evolving Evidence in the Treatment of Primary and Recurrent Posterior Cruciate Ligament Injuries, Part 2 - Surgical Techniques, Outcomes and Rehabilitation.” Knee Surg Sports Traumatol Arthrosc 2020. Accepted for Publication.
  • Winkler PW, Hughes JD, Musahl V. “Editorial Commentary: Respect the Posterior Tibial Slope and Make Slope-Reducing Osteotomies an Integral Part of the Surgical Repertoire.” Arthroscopy: The Journal of Arthroscopic & Related Surgery 2020; 36(10): 2728-2730.
  • Hughes JD, Lawton CD, Nawabi DH, Pearle AD, Musahl V. “Anterior Cruciate Ligament Repair: The Current Status.” JBJS. 2020 Sep 16.
  • Kane G, LeVasseur, Hughes JD, Anderst W, Lin A. “Arthroscopic Superior Capsular Reconstruction for Massive Irreparable Rotator Cuff Tears: Clinical Outcomes and In Vivo Assessment of Kinematic Effects.” UPMC Ortho Restore. April 27, 2020.
  • Diermeier T, Tisherman R, Hughes JD, Tullman M, Coffey EB, Fink C, Lynch A, Fu FH, Musahl V. “Quadriceps tendon anterior cruciate ligament reconstruction.” Knee Surg Sports Traumatol Arthrosc 2020.
  • Hughes JD, Vaswani R, Gibbs CM, Tisherman RT, Musahl V. “ACL Reconstruction with a Partial Thickness Quadriceps Tendon Graft Secured with a Continuous Loop Endobutton.” Arthroscopy Techniques 2020.  April 3.
  • Hughes JD, Rauer T, Gibbs CM, Musahl V. “Diagnosis and Treatment of Rotatory Knee Instability.” Journal of Experimental Orthopaedics 2019;6(1):1-10.
  • Hughes JD, Burnham JM, Hirsh A, Musahl V, Fu FH, Irrgang JJ, Lynch AD. “Comparison of Short-Term Biodex Results after Anatomic ACL Reconstruction Between Three Autografts.”  The Orthopaedic Journal of Sports Medicine, 7(5), 2325967119847630. doi: 10.1177/2325967119847630.
  • Hughes JD, Stahl DL. “Ischial Tuberosity Avulsion Fracture Nonunions in the Adolescent Population Treated With a Posterior Column Screw: A Case Series of 2 Patients.”  Journal of Orthopaedic Surgery 2019.
  • Hughes JD, Shin JJ, Albers M, Musahl V, Fu F.  “A Closer Look at the Relationship Between Industry and Orthopedic Sports Medicine Surgeons.”  The Orthopaedic Journal of Sports Medicine 2019, 7(1), 2325967118823175. doi: 10.1177/2325967118823175
  • Pfeiffer TR, Burnham JM, Kanakamedala AC, Hughes JD, Zlotnicki J, Popchak A, Debski RE, Musahl V.  “Distal Femur Morphology Affects Rotatory Knee Instability in Patients with Anterior Cruciate Ligament Ruptures.” Knee Surgery, Sports Traumatology, Arthroscopy 2018 Oct 29:1-6.
  • Pfeiffer TR, Burnham JM, Hughes JD, Kanakamedala AC, Herbst E, Popchak A, Shafizadeh S, Irrgang JJ, Debski RE, Musahl V. “An Increased Lateral Femoral Condyle Ratio Femur is a Risk Factor for Anterior Cruciate Ligament Injury.”  J Bone Joint Surg Am 2018 May 16;100(10):857-864. doi: 10.2106/JBJS.17.01011
  • Hughes JD, Mittwede P. “Making the Most of Protected Research Time in Residency” AAOS Now May 2018.
  • Lucidi GA, Hughes JD, Herbst E, Burnham JM, Musahl V. “Role of the Anterolateral Complex in Rotatory Instability of the Anterior Cruciate Ligament Deficient Knee” Ann Joint 2017. doi: 10.21037/aoj.2017.06.09.
  • Hughes JD, Hughes JL, Bartley JH, Hamilton WP, Brennan KL. “Infection Rates in Arthroscopic Versus Open Rotator Cuff Repair” Orthopaedic Journal of Sports Medicine 2017;5(7): 2325967117715416.  

Research Interests

  • Rotatory Knee Instability
  • Anatomic ACL Reconstruction
  • Multiligament Knee Injuries
  • Meniscus Tears
  • Knee Kinematics
  • Shoulder Instability
  • Superior Capsular Reconstruction
  • Total Shoulder Arthroplasty
  • ​Shoulder Kinematics

Research Grants

Albert B. Ferguson Orthopaedic Fund of the Pittsburgh Foundation 2020 ($5,000)
Hughes JD,
Albers M, Krivoniak A, Ghodadra A, Kimatura G, Lin A.
“The Use of CT Scans with 3D Modeling in Revision Shoulder Arthroplasty”

W81XWH-17-2-0073 (Irrgang, Musahl)
09/30/2017 – 09/29/2021
Department of Defense $2,054,687 (total award)
Surgical Timing and Rehabilitation for MLKIs: A Multicenter Integrated Clinical Trial
The overall purpose of this project is to determine when it is best to do surgery (within 6 weeks of injury or 3 to 4 months after injury) and when to start rehab (immediately or 4 weeks after surgery) for the treatment of knee dislocations on how long it takes to resume pre-injury military duty, work, and sports.
Role: Co-Investigator

U01AR076144 (Irrgang, Musahl)
09/17/19 - 08/31/2024
National Institute of Health $705,076 (total award)
STABILITY 2: ACL Reconstruction +/- Lateral Tenodesis with Patellar vs. Quad Tendon
Brief Description of Project Aims: Determine if graft type (QT, BPTB, HT) with or without a lateral extra-articular tenodesis (LET) affects: 1) Rate of graft failure 2 years after anterior cruciate ligament reconstruction (ACLR); 2) Patient-reported outcomes, muscle function, performance-based measures of function (hop tests, drop vertical jump) and return to sports; 3) Intervention-related donor site morbidity, complications and adverse outcomes and 4) Cost-effectiveness of ACLR and LET.
Role: Co-Investigator