Department of Orthopaedic Surgery

Drs. Musahl and Irrgang to Lead Stability II, an International Multi-Centre Prospective Clinical Study

The University of Pittsburgh (PI Irrgang, and Musahl), in conjunction with Western Ontario University (PI Getgood), has been awarded a  $3.2 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) to conduct a prospective randomized international multicenter Clinical Trial to determine if the use of the quadriceps tendon versus patellar tendon, either with or without a lateral extra-articular tenodesis, reduces the risk of re-injury of the ACL, results in less symptoms and better function and quality of life and an improved ability to return to sports.  

This study, Stability II, will include 21 sites across the USA, Canada, and Europe and will assess outcomes over a two-year period. At its conclusion, Investigators will be able to definitively determine the best graft choice for young patients at high risk of re-rupture following anterior cruciate ligament reconstruction (ACLR), which will ultimately lead to positive effects on return to pre-injury level of sports activity and quality of life.